Install Docker Desktop

Docker allows you to run software inside an isolated “container image” on your computer with all of that application’s needed dependencies. Make sure to install the version for your operating system.

• Mac-Intel
• Mac-AppleChip

MIRA Installation

• Open Docker Desktop, and once it is running:

Open Settings -> Features in development -> Experimental Features:

• Ensure “Access Experimental Features” and “Enable backround SBOM Indexing” are both checked on

Next, in Beta Features, enable “Use Rosetta for x86/amd66 emulation on Apple Silicon”. This will help MIRA run faster and remain more stable

Save these settings by clicking “Apply & restart”

Open the terminal, and copy/paste these commands

mkdir ~/FLU_SC2_SEQUENCING

cd ~/FLU_SC2_SEQUENCING

curl https://raw.githubusercontent.com/CDCgov/MIRA/prod/docker-compose-git.yml | sed "s%/path/to/data%$(pwd)/%g" > docker-compose.yml

sudo docker-compose up -d

You are now running MIRA! You can proceed to Running MIRA

If these instructions show errors, please refer to our Troubleshooting page

Install a sequence viewer

• Jalview