Seasonal Flu Sequence References
Curated GISAID EPI_SET genetic sequence references for seasonal influenza (H3N2, H1N1pdm09, B Victoria), including Complete and Contemporary per-segment datasets plus ferret antisera reagent references.
Genetic References
Genetic sequence references for seasonal influenza (H3N2, H1N1pdm09, B Victoria). Two categories of genetic reference datasets exist, “Complete” and “Contemporary”. “Complete” datasets have references across a longer term of evolutionary history of each seasonal influenza type. “Contemporary” datasets are limited to more recent genetic breakpoints for each seasonal influenza type.
These datasets are generated on a per-segment level. EPI_SET searches will return all samples from the set, but only the specific segment should be downloaded for sequences.
Complete
| Subtype | Data Window |
|---|---|
| H1N1pdm09 | From the 2009 pandemic onwards |
| H3N2 | From 2008 onwards |
| B Victoria | From 2008 onwards |
Datasets:
Contemporary
| Subtype | Data Window |
|---|---|
| H1N1pdm09 | From the origin of 6B.1A.5a (~2018, Subclade A) onwards |
| H3N2 | From the origin of 3C.2a1b.2 (mid-2017, Subclade E) onwards |
| B Victoria | From the origin of V1A.3 (~2017, Subclade A.3) onwards |
Datasets:
Reagent References
Reagent references are samples representing current CDC ferret antisera used in phenotypic tests.
| Subtype | EPI_SET | DOI | Sample Number |
|---|---|---|---|
| H3N2 | EPI_SET_260714ep | https://doi.org/10.55876/gis8.260714ep | 144 |
| H1N1pdm09 | EPI_SET_260714xo | https://doi.org/10.55876/gis8.260714xo | 107 |
| B Victoria | EPI_SET_260714as | https://doi.org/10.55876/gis8.260714as | 111 |
Notes on Datasets
- Datasets will be updated quarterly
- These current datasets were generated on 2026-07-13